Mike Pratt and the Fighting Irish dominated the Oakfield-Alabama Hornets from Notre Dame's opening drive, when Pratt carried the ball on each snap resulting in a touchdown.
In all, Pratt had 234 yards on 18 carries and scored three times.
Notre Dame won 36-0 in the Saturday afternoon match-up.
It was also a big game for Nick Taylor, who had 16 carries for 118 yards and two touchdowns.
In all, Notre Dame rushed for 433 yards on 50 attempts.
On defense, Taylor also had six tackles.
The Hornets drop to 0-3 and Notre Dame moves to 2-1.
In other Genesee County football action Friday and Saturday:
Alexander (0-3) fell to Barker (1-2), 20-17. Jared Quinn threw two touchdown passes to John Winiecki for Alexander.
Pembroke (3-0) defeated Elba/Byron-Bergen (2-1) 6-3. For Pembroke, Caine Cole had 155 yards on 32 attempts, while Dylan Bordonaro had 85 yards on 13 rushes for Elba/Byron-Bergen.
After two shutout wins to open the season, Holley (2-1) lost to Attica (2-1), 26-23. For Attica, Brad Clark rushed for 247 yards on 32 carries. He scored twice, including the winning touchdown.
Le Roy (2-1) dominated Perry (1-2), 56-20. Tommy McQuillen rushed for 186 yards on 10 touches and scored four touchdowns. Defensively, Brad Morgan forced a fumble and had nine tackles. Austin Steinbrenner added six tackles to go with two interceptions.
In a Saturday night game at Van Detta Stadium, the Batavia Blue Devils were 0-3 after losing to St. Mary's (2-1), 21-14.
More pictures from OA at ND after the jump:
